2F-NENDCK
Canetone
Overview
2F-NENDCK (Canetone) is a novel fluorinated arylcyclohexylamine representing cutting-edge dissociative research chemical development.
The history of 2F-NENDCK is linked to the development of dissociative anesthetics, beginning with the discovery of phencyclidine (PCP) in 1926 and ketamine in 1962. These compounds revealed that NMDA receptor antagonism could produce unique dissociative states distinct from other classes of psychoactive substances. 2F-NENDCK represents a continuation of research into this pharmacological mechanism. Research into arylcyclohexylamine and related dissociatives intensified in recent decades as scientists sought to understand the relationship between molecular structure and NMDA receptor binding affinity. 2F-NENDCK emerged as a compound of interest for studying dissociative mechanisms, anesthetic properties, and neuroprotective effects. The compound has been characterized using advanced analytical techniques including mass spectrometry and nuclear magnetic resonance spectroscopy. Modern research utilizing 2F-NENDCK focuses on understanding NMDA receptor pharmacology, glutamatergic neurotransmission, and potential therapeutic applications. The compound serves as a valuable reference standard in forensic toxicology and analytical chemistry, contributing to the development of detection methods for novel dissociatives in biological samples.
2F-NENDCK acts as an NMDA (N-methyl-D-aspartate) receptor antagonist, blocking glutamate neurotransmission. This mechanism produces characteristic dissociative effects and makes it valuable for studying glutamatergic system function.
2F-NENDCK holds significant value in scientific research due to its well-characterized properties and legal accessibility in several jurisdictions. This enables comprehensive pharmacological studies and analytical method development.
High-purity 2F-NENDCK (≥98% by HPLC) serves as a crucial reference standard in research laboratories, quality control testing, and academic research settings. Its consistent quality makes it ideal for method development and validation.
Technical Specifications
Why Researchers Choose 2F-NENDCK
🔬NMDA Receptor Studies
2F-NENDCK is utilized in research investigating NMDA receptor antagonism and its effects on glutamatergic neurotransmission. As a reference standard, it enables precise analytical quantification.
🧬Anesthesia Research
Researchers study 2F-NENDCK to understand dissociative anesthetic mechanisms and structure-activity relationships in arylcyclohexylamine compounds. This supports development of analytical detection methods.
📊Quality Assurance
Laboratories use high-purity 2F-NENDCK for method validation, equipment calibration, and developing screening protocols for dissociative compounds in various matrices.
Research Applications
2F-NENDCK is commonly used in various scientific research contexts:
Important: All research applications are for in vitro and analytical purposes only. Not for human or veterinary use.
Chemical Properties
Solubility Data
Analytical Methods
External Chemical Databases
Safety & Hazard Information
Hazard Statements (H):
- •H302: Harmful if swallowed
- •H315: Causes skin irritation
- •H319: Causes serious eye irritation
- •H335: May cause respiratory irritation
Precautionary Statements (P):
- •P261: Avoid breathing dust/fume/gas/mist/vapors/spray
- •P264: Wash hands thoroughly after handling
- •P280: Wear protective gloves/protective clothing/eye protection/face protection
- •P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell
Common Effects
Legal Status by Country
Legal for Research
Click any country to view detailed legal information and shipping regulations.
Frequently Asked Questions
Q:What is 2F-NENDCK used for in research?
2F-NENDCK is primarily used as an analytical reference standard in forensic toxicology, pharmacological research, quality control testing, and method development. It is NOT intended for human or veterinary use.
Q:How should 2F-NENDCK be stored?
Store 2F-NENDCK at -20°C in a dark, dry environment. Protect from light and moisture to maintain stability. When stored properly, research chemicals have a shelf life of approximately 2 years. Always use amber glass vials with proper sealing.
Q:Is 2F-NENDCK legal in my country?
Legal status varies by jurisdiction. 2F-NENDCK is legal for research purposes in several EU countries including Ireland, Italy, Netherlands as of 2026. Always verify current regulations in your specific location before ordering.
Q:What analytical methods are used to test 2F-NENDCK purity?
High-Performance Liquid Chromatography with UV detection (HPLC-UV) is the primary method for purity analysis. Additional confirmation methods include Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Mass Spectrometry (LC-MS/MS), and Nuclear Magnetic Resonance (NMR) spectroscopy.
Q:What is the minimum purity guaranteed for EuroChems 2F-NENDCK?
All EuroChems 2F-NENDCK products are guaranteed to be ≥98% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis (COA) confirming purity specifications.
Related Research
Resources
Available in multiple languages upon request
Safety Notice
This compound is for research purposes only. Not for human consumption. Always use proper safety equipment and follow all applicable regulations.