Overview
6-EAPB is a benzofuran analog studied for entactogenic effects and monoamine release. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
The history of 6-EAPB is connected to research into entactogens and empathogens, a class of compounds that became prominent following the synthesis and characterization of MDMA in the early 20th century. Scientists investigating benzofuran and related compounds sought to understand how structural modifications affect serotonin and dopamine release mechanisms. 6-EAPB emerged as part of this systematic research. Research into novel empathogens intensified as chemists explored alternatives to classical entactogens, investigating compounds with potentially different pharmacological profiles. 6-EAPB became a subject of interest for its effects on monoamine neurotransmitter systems and potential applications in neuroscience research. The compound has been studied for its interactions with serotonin and dopamine transporters and receptors. Contemporary research utilizing 6-EAPB focuses on understanding empathogenic mechanisms, monoamine release pharmacology, and structure-activity relationships. The compound serves as an important analytical reference standard and contributes to research on social cognition, emotional processing, and neurotransmitter dynamics in laboratory settings.
6-EAPB acts primarily by promoting release of serotonin, dopamine, and norepinephrine while also inhibiting their reuptake. This dual mechanism produces characteristic empathogenic and entactogenic effects valuable for neuropharmacology research.
6-EAPB holds significant value in scientific research due to its well-characterized properties and legal accessibility in several jurisdictions. This enables comprehensive pharmacological studies and analytical method development.
High-purity 6-EAPB (≥98% by HPLC) serves as a crucial reference standard in research laboratories, quality control testing, and academic research settings. Its consistent quality makes it ideal for method development and validation.
Technical Specifications
Why Researchers Choose 6-EAPB
🔬Monoamine Release Research
6-EAPB is studied for its effects on serotonin, dopamine, and norepinephrine release mechanisms. As a reference standard, it enables analytical method development for entactogenic compounds.
🧬Empathogenic Pharmacology
Researchers investigate 6-EAPB to understand structure-activity relationships in benzofuran and related entactogens, supporting studies on emotional processing and social cognition.
📊Analytical Standards
High-purity 6-EAPB serves as a crucial reference for forensic laboratories and quality control testing, enabling detection method validation for novel empathogens.
Research Applications
6-EAPB is commonly used in various scientific research contexts:
Important: All research applications are for in vitro and analytical purposes only. Not for human or veterinary use.
Chemical Properties
Solubility Data
Analytical Methods
External Chemical Databases
Safety & Hazard Information
Hazard Statements (H):
- •H302: Harmful if swallowed
- •H315: Causes skin irritation
- •H319: Causes serious eye irritation
- •H335: May cause respiratory irritation
Precautionary Statements (P):
- •P261: Avoid breathing dust/fume/gas/mist/vapors/spray
- •P264: Wash hands thoroughly after handling
- •P280: Wear protective gloves/protective clothing/eye protection/face protection
- •P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell
Common Effects
Legal Status by Country
Legal for Research
Click any country to view detailed legal information and shipping regulations.
Frequently Asked Questions
Q:What is 6-EAPB used for in research?
6-EAPB is primarily used as an analytical reference standard in forensic toxicology, pharmacological research, quality control testing, and method development. It is NOT intended for human or veterinary use.
Q:How should 6-EAPB be stored?
Store 6-EAPB at -20°C in a dark, dry environment. Protect from light and moisture to maintain stability. When stored properly, research chemicals have a shelf life of approximately 2 years. Always use amber glass vials with proper sealing.
Q:Is 6-EAPB legal in my country?
Legal status varies by jurisdiction. 6-EAPB is legal for research purposes in several EU countries including Ireland, Italy as of 2026. Always verify current regulations in your specific location before ordering.
Q:What analytical methods are used to test 6-EAPB purity?
High-Performance Liquid Chromatography with UV detection (HPLC-UV) is the primary method for purity analysis. Additional confirmation methods include Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Mass Spectrometry (LC-MS/MS), and Nuclear Magnetic Resonance (NMR) spectroscopy.
Q:What is the minimum purity guaranteed for EuroChems 6-EAPB?
All EuroChems 6-EAPB products are guaranteed to be ≥98% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis (COA) confirming purity specifications.
Related Research
Resources
Available in multiple languages upon request
Safety Notice
This compound is for research purposes only. Not for human consumption. Always use proper safety equipment and follow all applicable regulations.