O-DSMT

O-DSMT is an opioid analgesic and tramadol metabolite used in research on mu-opioid receptor pharmacology and pain management studies.

The history of O-DSMT is connected to opioid research extending from morphine's isolation in 1804 to modern synthetic opioid development. Scientists have extensively investigated how structural modifications to opioid scaffolds affect mu, delta, and kappa opioid receptor binding and activity. O-DSMT represents a product of this ongoing research into novel opioid compounds. Research into synthetic opioids has focused on understanding structure-activity relationships at opioid receptors, metabolism, and pharmacokinetics. O-DSMT emerged as a compound of interest for studying these relationships and for use as an analytical reference standard in forensic toxicology. The compound has been characterized using advanced analytical techniques including mass spectrometry and chromatography. Modern research applications of O-DSMT include studies on opioid receptor pharmacology, analgesic mechanisms, and the development of detection methods for novel opioids in biological samples. The compound serves as a valuable tool in analytical chemistry and pain research, contributing to our understanding of opioid receptor function and pharmaceutical development.

O-DSMT acts primarily as an agonist at mu-opioid receptors, producing analgesic effects. This mechanism makes it valuable for research on opioid receptor pharmacology, pain management, and forensic detection method development.

O-DSMT holds significant value in scientific research due to its well-characterized properties and legal accessibility in several jurisdictions. This enables comprehensive pharmacological studies and analytical method development.

High-purity O-DSMT (≥98% by HPLC) serves as a crucial reference standard in research laboratories, quality control testing, and academic research settings. Its consistent quality makes it ideal for method development and validation.