Compounds / Category Guide

Dissociatives

Research chemical guide: effects, safety, and compound information

What are Dissociatives?

Dissociatives are substances that produce feelings of detachment from one's body and environment. They typically work as NMDA receptor antagonists.

Common Effects

Dissociation
Analgesia
Altered sensory perception
Euphoria
Out-of-body experiences

Safety Information

Can cause confusion and motor impairment. Use in safe environment only.

Dissociatives in Our Database (21 compounds)

DCK

Deschloroketamine

DCK is an arylcyclohexylamine dissociative that acts as an NMDA receptor antagonist. Structurally related to ketamine but with longer duration.

Duration: 2-4 hours
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2F-NENDCK

Canetone

2F-NENDCK (Canetone) is a novel fluorinated arylcyclohexylamine representing cutting-edge dissociative research chemical development.

Duration: 3-5 hours
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3D-MXE

3-Desoxy-Methoxetamine

3D-MXE is a dissociative related to MXE, available in convenient pellet form for precise dosing. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 3-6 hours
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O-PCE

O-PCE

O-PCE is a dissociative anesthetic structurally related to PCP and ketamine. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 4-8 hours
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HXE

Hexetamine

HXE is a novel dissociative research chemical in the arylcyclohexylamine class. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 3-5 hours
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2-FDCK

2-Fluorodeschloroketamine

2-FDCK is a fluorinated ketamine analog used in NMDA receptor research and dissociative anesthetic studies.

Duration: 2-4 hours
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DMXE

Deoxymethoxetamine

DMXE is a dissociative research chemical in the arylcyclohexylamine class, used for studying NMDA receptor antagonism.

Duration: 4-7 hours
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3-MeO-PCP

3-Methoxyphencyclidine

3-MeO-PCP is a dissociative used in research on PCP-type NMDA receptor antagonists and their pharmacological properties.

Duration: 4-8 hours
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3-MeO-PCE

3-Methoxyeticyclidine

3-MeO-PCE is an arylcyclohexylamine dissociative studied for NMDA receptor research and pharmacology.

Duration: 4-8 hours
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3-HO-PCP

3-Hydroxyphencyclidine

3-HO-PCP is a dissociative anesthetic analog used in pharmacological research on NMDA receptor mechanisms.

Duration: 5-8 hours
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3-HO-PCE

3-Hydroxyeticyclidine

3-HO-PCE is a dissociative research chemical used for studying hydroxylated arylcyclohexylamine pharmacology.

Duration: 4-7 hours
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3-MeO-PCE

Methoxyeticyclidine

3-MeO-PCE is a dissociative anesthetic analog used for NMDA receptor research and arylcyclohexylamine pharmacology studies.

Duration: 4-8 hours
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MXPr

Methoxpropamine

MXPr is a novel dissociative in the arylcyclohexylamine class, studied for NMDA antagonist properties.

Duration: 3-5 hours
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MXiPr

Methoxisopropamine

MXiPr is a dissociative research chemical used in studies on arylcyclohexylamine pharmacology and NMDA receptor function.

Duration: 3-6 hours
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Ketamine

Ketamine is a well-studied dissociative anesthetic used extensively in NMDA receptor research and pharmaceutical development. Serves as a reference standard for arylcyclohexylamine studies.

Duration: 1-3 hours
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MXE

Methoxetamine

MXE is a dissociative anesthetic analog historically used in NMDA receptor research and arylcyclohexylamine pharmacology.

Duration: 3-6 hours
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Ephenidine

Ephenidine is a diarylethylamine dissociative used in research on NMDA receptor antagonism and novel dissociative mechanisms.

Duration: 4-8 hours
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Diphenidine

Diphenidine is a diarylethylamine dissociative studied for its NMDA antagonist properties and structure-activity relationships.

Duration: 5-8 hours
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MXPr

Methoxpropamine

MXPr is a novel arylcyclohexylamine dissociative used for NMDA receptor research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 3-5 hours
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2-Oxo-PCE

2-Oxo-PCE is an arylcyclohexylamine dissociative studied for NMDA receptor pharmacology. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 4-7 hours
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FDCK

Fluoroketamine

FDCK is a fluorinated ketamine analog used in dissociative anesthetic research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 2-4 hours
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Research Applications

Dissociatives are studied in various research contexts including pharmacology, neuroscience, and consciousness studies. Researchers use these compounds to investigate:

  • Receptor binding profiles and affinity studies
  • Structure-activity relationships (SAR)
  • Metabolic pathways and pharmacokinetics
  • Comparative pharmacology with related compounds

Laboratory Safety Guidelines

Handling Precautions

  • Always use proper laboratory equipment and personal protective equipment (PPE)
  • Work in a well-ventilated area or fume hood
  • Use analytical scales for precise measurements
  • Store compounds according to manufacturer specifications

Testing

Always verify substance identity using reagent testing kits or analytical methods such as:

  • Gas chromatography-mass spectrometry (GC-MS)
  • Liquid chromatography-mass spectrometry (LC-MS)
  • Nuclear magnetic resonance (NMR) spectroscopy
  • Reagent color testing (Marquis, Ehrlich, etc.)

Legal Considerations

The legal status of Dissociatives varies significantly by jurisdiction. Many countries have implemented analogue acts or blanket bans on entire chemical families.

Important: Always verify the legal status of specific compounds in your jurisdiction before ordering. EuroChems only ships to countries where compounds are legal for research purposes.

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