Compounds / Category Guide

Empathogens

Research chemical guide: effects, safety, and compound information

What are Empathogens?

Empathogens (entactogens) are substances that produce feelings of emotional openness, empathy, and enhanced sensory perception. They typically affect serotonin, dopamine, and norepinephrine systems.

Common Effects

Euphoria
Empathy
Emotional openness
Enhanced sensory perception
Sociability

Safety Information

Can cause serotonin syndrome when combined with other serotonergic drugs. Ensure proper hydration.

Empathogens in Our Database (10 compounds)

6-APB

6-(2-Aminopropyl)benzofuran

6-APB is a benzofuran entactogen used in research on serotonin and dopamine release mechanisms. Structurally related to MDA.

Duration: 6-8 hours
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5-APB

5-(2-Aminopropyl)benzofuran

5-APB is a benzofuran compound studied for its empathogenic effects and serotonin-releasing properties.

Duration: 6-8 hours
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5-MAPB

5-(2-Methylaminopropyl)benzofuran

5-MAPB is an entactogenic benzofuran used in pharmacological studies on serotonin release and empathogenic effects.

Duration: 5-7 hours
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6-APDB

6-(2-Aminopropyl)-2,3-dihydrobenzofuran

6-APDB is a benzofuran analog studied for entactogenic properties and monoamine neurotransmitter research.

Duration: 5-7 hours
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5-APDB

5-APDB is a benzofuran entactogen studied for serotonin and dopamine release mechanisms. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 5-7 hours
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5-EAPB

5-EAPB is an ethylated benzofuran entactogen used in empathogen pharmacology research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 5-7 hours
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6-EAPB

6-EAPB is a benzofuran analog studied for entactogenic effects and monoamine release. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 6-8 hours
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MDAI

5,6-Methylenedioxy-2-aminoindane

MDAI is an aminoindane entactogen used in research on selective serotonin release. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 4-6 hours
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6-MAPB

6-MAPB is a benzofuran entactogen used in research on methylated empathogen analogs. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 5-7 hours
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5-MAPDB

5-MAPDB is a benzodifuran entactogen studied for empathogenic pharmacology research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.

Duration: 5-7 hours
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Research Applications

Empathogens are studied in various research contexts including pharmacology, neuroscience, and consciousness studies. Researchers use these compounds to investigate:

  • Receptor binding profiles and affinity studies
  • Structure-activity relationships (SAR)
  • Metabolic pathways and pharmacokinetics
  • Comparative pharmacology with related compounds

Laboratory Safety Guidelines

Handling Precautions

  • Always use proper laboratory equipment and personal protective equipment (PPE)
  • Work in a well-ventilated area or fume hood
  • Use analytical scales for precise measurements
  • Store compounds according to manufacturer specifications

Testing

Always verify substance identity using reagent testing kits or analytical methods such as:

  • Gas chromatography-mass spectrometry (GC-MS)
  • Liquid chromatography-mass spectrometry (LC-MS)
  • Nuclear magnetic resonance (NMR) spectroscopy
  • Reagent color testing (Marquis, Ehrlich, etc.)

Legal Considerations

The legal status of Empathogens varies significantly by jurisdiction. Many countries have implemented analogue acts or blanket bans on entire chemical families.

Important: Always verify the legal status of specific compounds in your jurisdiction before ordering. EuroChems only ships to countries where compounds are legal for research purposes.

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