Phenethylamines
Research chemical guide: effects, safety, and compound information
What are Phenethylamines?
Phenethylamines are a large class of compounds that include many psychedelics and entactogens. Research phenethylamines are studied for their effects on serotonin receptors and structure-activity relationships.
Common Effects
Safety Information
Highly potent compounds. Many have very long durations (12-30 hours). Always verify dosing.
Phenethylamines in Our Database (27 compounds)
2C-B
4-Bromo-2,5-dimethoxyphenethylamine
2C-B is a phenethylamine used extensively in pharmacological research on serotonin 5-HT2 receptor mechanisms and psychedelic effects.
2C-B-FLY
8-Bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine
2C-B-FLY is a benzodifuran phenethylamine studied for structure-activity relationships in psychedelic research.
2C-C
4-Chloro-2,5-dimethoxyphenethylamine
2C-C is a phenethylamine compound used in research on 5-HT2A receptor activation and psychedelic pharmacology.
2C-D
2,5-Dimethoxy-4-methylphenethylamine
2C-D is a phenethylamine used in psychopharmacology research, particularly for studying dose-response relationships in psychedelics.
2C-E
4-Ethyl-2,5-dimethoxyphenethylamine
2C-E is a phenethylamine compound studied for its effects on serotonin receptors and psychedelic intensity dose curves.
2C-I
4-Iodo-2,5-dimethoxyphenethylamine
2C-I is a potent phenethylamine used in research on halogenated psychedelic compounds and receptor binding affinity.
2C-P
4-Propyl-2,5-dimethoxyphenethylamine
2C-P is a phenethylamine with an extended duration, used in long-acting psychedelic pharmacology research.
25I-NBOMe
2C-I-NBOMe
25I-NBOMe is a highly potent 5-HT2A receptor agonist used in research on psychedelic receptor pharmacology and structure-activity relationships.
25B-NBOMe
2C-B-NBOMe
25B-NBOMe is an N-benzyl phenethylamine used in research on ultra-potent 5-HT2A receptor agonists. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
25C-NBOMe
2C-C-NBOMe
25C-NBOMe is a phenethylamine derivative used in studying N-benzyl substitution effects on serotonin receptor pharmacology.
DOI
2,5-Dimethoxy-4-iodoamphetamine
DOI is a substituted amphetamine used in research on 5-HT2A receptor pharmacology and long-acting psychedelics.
DOC
2,5-Dimethoxy-4-chloroamphetamine
DOC is an amphetamine-class psychedelic used in long-duration serotonin receptor research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
DOB
2,5-Dimethoxy-4-bromoamphetamine
DOB is a substituted amphetamine studied for its potent 5-HT2A receptor agonist properties and extended duration.
Mescaline
3,4,5-Trimethoxyphenethylamine
Mescaline is a naturally occurring phenethylamine used extensively in research on classical psychedelic mechanisms and serotonin pharmacology.
2C-T-2
2,5-Dimethoxy-4-ethylthiophenethylamine
2C-T-2 is a thiophenethylamine studied for sulfur-substituted psychedelic pharmacology. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
2C-T-7
2,5-Dimethoxy-4-propylthiophenethylamine
2C-T-7 is a substituted phenethylamine used in research on thio-substituted psychedelics. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
2C-T-4
2,5-Dimethoxy-4-isopropylthiophenethylamine
2C-T-4 is a thiophenethylamine studied for structure-activity relationships in psychedelic research.
25D-NBOMe
25D-NBOMe is an N-benzyl phenethylamine used in research on ultra-potent 5-HT2A agonists. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
25E-NBOMe
25E-NBOMe is an NBOMe compound studied for high-potency serotonin receptor pharmacology. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
DOM
2,5-Dimethoxy-4-methylamphetamine
DOM is a substituted amphetamine used extensively in research on long-acting psychedelics and 5-HT2A receptor pharmacology.
Escaline
3,5-Dimethoxy-4-ethoxyphenethylamine
Escaline is a mescaline analog studied for alkoxy-substituted phenethylamine pharmacology. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
Proscaline
3,5-Dimethoxy-4-propoxyphenethylamine
Proscaline is a mescaline derivative used in research on alkoxy phenethylamine structure-activity relationships.
Allylescaline
3,5-Dimethoxy-4-allyloxyphenethylamine
Allylescaline is a substituted phenethylamine studied for mescaline analog pharmacology. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
2C-H
2,5-Dimethoxyphenethylamine
2C-H is a simple phenethylamine used in structure-activity relationship research as a baseline compound.
2C-N
4-Nitro-2,5-dimethoxyphenethylamine
2C-N is a nitro-substituted phenethylamine studied for electron-withdrawing group effects on pharmacology.
25P-NBOMe
25P-NBOMe is an N-benzyl phenethylamine used in high-potency 5-HT2A receptor research. This compound is widely used in analytical chemistry research as a reference standard and for pharmacological studies investigating receptor mechanisms and structure-activity relationships.
Bromo-DragonFLY
DOB-DFLY
Bromo-DragonFLY is a benzodifuran phenethylamine studied for extremely long-acting psychedelic effects.
Research Applications
Phenethylamines are studied in various research contexts including pharmacology, neuroscience, and consciousness studies. Researchers use these compounds to investigate:
- Receptor binding profiles and affinity studies
- Structure-activity relationships (SAR)
- Metabolic pathways and pharmacokinetics
- Comparative pharmacology with related compounds
Laboratory Safety Guidelines
Handling Precautions
- Always use proper laboratory equipment and personal protective equipment (PPE)
- Work in a well-ventilated area or fume hood
- Use analytical scales for precise measurements
- Store compounds according to manufacturer specifications
Testing
Always verify substance identity using reagent testing kits or analytical methods such as:
- Gas chromatography-mass spectrometry (GC-MS)
- Liquid chromatography-mass spectrometry (LC-MS)
- Nuclear magnetic resonance (NMR) spectroscopy
- Reagent color testing (Marquis, Ehrlich, etc.)
Legal Considerations
The legal status of Phenethylamines varies significantly by jurisdiction. Many countries have implemented analogue acts or blanket bans on entire chemical families.
Important: Always verify the legal status of specific compounds in your jurisdiction before ordering. EuroChems only ships to countries where compounds are legal for research purposes.
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