2C-C

2C-C (2,5-dimethoxy-4-chlorophenethylamine) is a synthetic psychedelic compound belonging to the phenethylamine class. This compound was initially synthesized by chemist Alexander Shulgin and described in the book “PiHKAL” (Phenethylamines I Have Known and Loved). Classified as a psychedelic substance, 2C-C shares structural similarities with other compounds in the 2C family, such as 2C-I, 2C-B, and 2C-E. It is primarily known for its mild effects and relatively short duration compared to other psychedelics, making it an intriguing subject for research and discussion in the context of psychoactive compounds.

Chemical Structure and Properties

The molecular formula of 2C-C is C10H14ClNO2, featuring a phenethylamine core with two methoxy groups (-OCH3) at the 2 and 5 positions and a chlorine atom (-Cl) at the 4 position of the benzene ring. Its molecular weight is approximately 215.68 g/mol. The placement of these functional groups influences its pharmacological activity and receptor binding affinity. The structure of 2C-C contributes to its properties as a serotonergic compound, with its effects primarily mediated through 5-HT2A receptor agonism.

2C-C typically presents as a white crystalline substance or powder in its pure form. It is known to be soluble in water and organic solvents, such as ethanol and dimethyl sulfoxide (DMSO). The standard dose of 2C-C ranges from 15 to 40 milligrams, depending on individual sensitivity and desired intensity of effects, while its duration of action usually spans 4 to 6 hours when taken orally.

Mechanism of Action

2C-C exerts its effects primarily by interacting with serotonin receptors, specifically the 5-HT2A receptor, within the central nervous system. Similar to other psychedelics, its activity at this receptor is believed to result in altered sensory perception, changes in mood, and a potential sense of introspection or enhanced awareness. Additionally, 2C-C may act on other serotonin receptor subtypes, such as 5-HT2C, contributing to its psychoactive profile.

One of the distinctive features of 2C-C is its relatively mild potency compared to other 2C compounds like 2C-I or 2C-B. Users and researchers have noted that the effects of 2C-C tend to be less stimulating and more relaxing, making it a preference for individuals seeking a gentler psychedelic experience.

Effects and Subjective Experience

The effects of 2C-C can vary significantly depending on the dosage, set, setting, and individual factors such as prior experience with psychedelics. Commonly reported effects include:

• Visual Alterations: Mild visual effects are typically observed, including enhanced colors, subtle patterning, and slight distortions in perception. The visuals associated with 2C-C are described as less intense compared to other psychedelics in the 2C family.
• Euphoria and Mood Elevation: Users often report feelings of euphoria, an enhanced sense of well-being, and emotional openness.
• Cognitive Effects: The substance may lead to introspection and altered thought patterns, though to a lesser extent than more potent psychedelics like LSD or psilocybin.
• Physical Sensations: Physical effects may include mild stimulation, a sense of bodily lightness or relaxation, and tingling sensations. Side effects such as nausea or tension are typically minimal when compared to other psychedelics.

Although 2C-C is generally considered to have a lower risk of overwhelming experiences, higher doses can still produce strong psychedelic effects, which may include confusion or feelings of depersonalization.

Safety and Toxicology

Research on the safety and toxicity of 2C-C remains limited, as it has not been widely studied in clinical settings. However, anecdotal reports and the compound’s pharmacological profile suggest that it has a relatively low toxicity when used responsibly in moderate doses. There is no documented evidence of fatal overdose from 2C-C alone, but as with any psychoactive substance, reckless use, mixing with other drugs, or underlying health conditions may introduce risks.

Physical side effects of 2C-C may include increased heart rate, elevated blood pressure, and mild gastrointestinal discomfort. Due to its serotonergic activity, combining 2C-C with other substances that affect serotonin levels, such as SSRIs or other psychedelics, could increase the risk of serotonin syndrome, a potentially dangerous condition.

Legal Status

The legal status of 2C-C varies across jurisdictions. In many countries, it is classified as a controlled substance, making its manufacture, possession, or distribution illegal. For example, 2C-C is listed under Schedule I of the United States Controlled Substances Act, indicating that it is considered to have no accepted medical use and a high potential for abuse. Similarly, it is prohibited in several European countries under analogous legislation. However, in some regions, its legal status may be ambiguous or unregulated, particularly where it is not explicitly listed in drug control laws.

Research and Applications

Although 2C-C is primarily known as a recreational substance, researchers have also considered its potential applications in therapeutic settings. Like other psychedelics, it may have potential for facilitating psychotherapy, particularly for conditions such as depression, anxiety, or PTSD. Its mild and manageable effects make it an appealing candidate for controlled studies and therapeutic exploration, though these possibilities are hindered by its legal restrictions and the lack of comprehensive research.

Storage and Stability

Proper storage is essential to preserve the stability and efficacy of 2C-C. The compound should be kept in an airtight container, away from heat, moisture, and light. Ideal storage conditions include a cool, dry place, such as a laboratory-grade desiccator. Degradation of the compound over time can diminish its effects and alter its chemical properties, so long-term storage in optimal conditions is recommended.

Summary

2C-C is a synthetic phenethylamine with mild psychedelic effects, primarily interacting with serotonin receptors to produce altered sensory perception and mood enhancement. Its relative gentleness, short duration, and manageable effects differentiate it from other substances in the 2C family. While its legal status restricts formal research, it holds potential for therapeutic applications in moderated environments. Proper handling, storage, and adherence to dosing guidelines are key for safe use and accurate research outcomes.