What is 2F-NENDCK (Canetone)?

2F-NENDCK (also known as Canetone or CanKet) is a novel arylcyclohexylamine research chemical. It is structurally related to 2-FDCK and Ketamine but features an N-ethyl substitution. It is used strictly for in-vitro laboratory research and forensic analysis.

Is 2F-NENDCK a legal replacement for 2-FDCK?

2F-NENDCK was developed to remain compliant in jurisdictions where 2-FDCK has been recently scheduled (such as the EU-wide ban). However, laws vary by country. We recommend checking your local 'Analog Act' or 'NpSG' regulations before ordering.

What is the purity of your 2F-NENDCK?

EuroChems stocks only high-purity 2F-NENDCK HCL, verified to be ≥98% pure via NMR and LC/MS testing to ensure consistent research results.

Does 2F-NENDCK have the same effects as 2-FDCK?

While similar in mechanism (NMDA antagonism), 2F-NENDCK is reported to be more potent and have a longer duration of action (4-6 hours) compared to the shorter-acting 2-FDCK. Researchers should adjust their protocols accordingly.

2F-NENDCK

Price range: € 14,95 through € 595,00

2F-NENDCK HCL (Canetone) is the premier novel dissociative reagent for 2026. Designed as a high-purity successor to 2-FDCK, this N-ethyl arylcyclohexylamine offers researchers a longer duration profile and distinct binding properties. Synthesized for stability and precision, it is the ideal candidate for NMDA receptor studies. Purity ≥98%. Lab use only.

SKU: N/A Categories: Dissociatives, New Products, Research Chemicals

Description
Additional information

2F-NENDCK (Canetone) – The Next Generation Arylcyclohexylamine

In the wake of recent regulatory shifts affecting 2-FDCK and HHC, the research community has been actively seeking a viable, high-purity successor. 2F-NENDCK HCL (often referred to as Canetone or CanKet) has emerged as the definitive answer for laboratory researchers across Europe.

This novel reagent is a structural analogue of Ketamine and 2-FDCK, specifically modified to offer a distinct pharmacological profile while remaining compliant in many jurisdictions where its predecessors are now restricted.

Chemical Properties & Structure

2F-NENDCK stands for 2-Fluoro-N-ethyl-nordeschloroketamine. It belongs to the arylcyclohexylamine class of dissociatives.

Systematic Name: 2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-1-one
Formula: C14H18FNO • HCl
Molecular Weight: 271.8 g/mol
Purity: ≥98% (Confirmed via NMR analysis)
Form: Crystalline HCL Powder

The key structural difference lies in the $N$ -ethyl group substitution. This modification, compared to the $N$ -methyl group found in 2-FDCK, significantly alters the compound’s binding affinity and duration, making it a unique subject for in-vitro NMDA receptor research.

Research Profile: What to Expect

Researchers familiar with 2-FDCK will find 2F-NENDCK to be a robust evolutionary step. Preliminary laboratory data suggests a higher potency by weight and a significantly extended duration of action compared to earlier analogues.

Duration: Early reports indicate a research window of 4–6 hours (considerably longer than 2-FDCK).
Potency: Higher binding affinity requires adjusted titration protocols.
Stability: High thermal stability makes it suitable for various spectrometric analyses (GC/MS, LC/MS).

Why Choose EuroChems for 2F-NENDCK?

We understand that consistency is the backbone of good science.

Third-Party Tested: Every batch is verified for purity to ensure no cross-contamination.
Discreet Shipping: We ship from within the EU using stealth packaging protocols.
Fresh Synthesis: Our stock is sourced directly from the lab, ensuring no degradation from long-term storage.

Disclaimer: This product is sold strictly for laboratory research and forensic applications. It is NOT for human consumption or veterinary use. Please check the laws in your specific country (e.g., The Netherlands, Germany, France) before ordering.