4-HO-MET Powder

4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine), also known as Methoxytryptamine, is a synthetic compound classified as a psychedelic substance. It is a derivative of the tryptamine family, structurally similar to psilocin, the active compound in psychedelic mushrooms. Recognized for its chemical complexity and research applications, 4-HO-MET primarily appeals to individuals conducting studies in psychopharmacology and neuroscience. This product is provided strictly for research purposes and is not intended for human consumption.

Chemical Properties and Composition

4-HO-MET is defined by the chemical formula C13H18N2O2, with a molecular weight of 234.3 g/mol. It consists of a tryptamine core substituted by a hydroxyl group at the 4th position on the indole ring and an N-methyl-N-ethyl group on the amine. This structural composition places 4-HO-MET within a subset of synthetic tryptamines acknowledged for their rigidity and psychoactive properties. The compound is typically supplied in powder form with a high level of purity (≥98%), ensuring reliable use for analytical and laboratory studies.

Appearance and Handling

4-HO-MET presents as a fine, crystalline white or off-white powder, depending on the specific synthesis process. The substance is stable under standard storage conditions, but to ensure longevity and integrity, it is recommended to store the product in a cool, dry environment, away from heat sources, light exposure, and moisture. Researchers working with 4-HO-MET should adhere to stringent laboratory practices, including the use of personal protective equipment (PPE) such as gloves, goggles, and lab coats, to maintain safety and prevent contamination.

Mechanism of Action

The effects of 4-HO-MET are studied in connection to its interaction with serotonin (5-HT) receptors, particularly the 5-HT2A receptor subtype. Its molecular structure facilitates its binding affinity to these receptors, inducing alterations in sensory perception, mood, and cognition in animal models and theoretical simulations. This interaction makes 4-HO-MET a key subject in studies targeting the neurochemical pathways involved in consciousness and perception.

Applications in Research

4-HO-MET powder is widely used within the research community for experimental purposes. Specific research areas may include:

1. Pharmacodynamics and Pharmacokinetics

Researchers study the compound’s behavior within biological systems, exploring absorption, distribution, metabolism, and excretion patterns to better understand its bioavailability and potency.

2. Neurochemistry Studies

Due to its serotonergic activity, 4-HO-MET is employed to explore the role of serotonin pathways in brain function, notably in relation to mood regulation, neural plasticity, and potential therapeutic applications.

3. Analytical Chemistry

The high purity of 4-HO-MET makes it an excellent candidate for developing and testing analytical methods such as liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS).

4. Behavioral Research in Animal Models

Experiments involving non-human subjects aim to delineate the behavioral and psychological effects of 4-HO-MET, enhancing our understanding of similar tryptamines’ mechanisms of action in complex biological systems.

Safety and Compliance

It is crucial to emphasize that 4-HO-MET powder is not approved for medical or recreational use. Possession, handling, or synthesis of 4-HO-MET must fully comply with applicable laws and regulations in the researcher’s jurisdiction. Laboratories and individuals purchasing this product are solely responsible for ensuring that its use aligns with ethical standards and legal requirements. Additionally, appropriate measures must be taken to avoid accidental exposure or misuse.

Packaging and Quality Assurance

Each batch of 4-HO-MET powder is produced under strictly controlled laboratory conditions, following rigorous quality assurance protocols. The compound is tested for purity, consistency, and composition using advanced analytical techniques. Packaging is designed to minimize contamination risks, with the product sealed in airtight containers and labeled for clarity.

Storage and Stability

To maximize the shelf life of 4-HO-MET powder, it is recommended to store the compound in an environment with a stable temperature, ideally between 2°C and 8°C. Long-term exposure to humidity and ultraviolet (UV) light can degrade the compound, potentially leading to loss of efficacy or changes in its chemical profile. Laboratories should regularly inspect the product to ensure it remains in optimal condition for research purposes.

Legal and Ethical Considerations

Before acquiring or working with 4-HO-MET powder, it is imperative for researchers to familiarize themselves with local, national, and international regulations regarding the handling of synthetic tryptamines. Studies involving controlled substances may require special permits or licenses, as dictated by regulatory authorities. Adhering to these guidelines ensures ethical compliance and minimizes legal risks for institutions and individuals.

Important Notice

The sale of 4-HO-MET powder is strictly limited to licensed professionals and institutions engaged in scientific research. It is not intended for any application involving humans, animals, or unauthorized experiments. By purchasing this product, users acknowledge their adherence to terms of use and regulatory obligations. Always prioritize safety, ethical standards, and scientific integrity when incorporating 4-HO-MET powder into experimental workflows.

By leveraging its distinctive properties, 4-HO-MET powder continues to be a valuable tool in advancing our understanding of neurochemistry and synthetic compound behavior. With careful handling and compliance, researchers can harness its potential for groundbreaking discoveries in medicinal chemistry and beyond.