4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine), also commonly known as Metocin, is a synthetic chemical compound belonging to the class of tryptamines. This substance is a derivative of psilocin, a naturally occurring psychedelic compound found in certain mushroom species. Due to its structural similarity to psilocin, 4-HO-MET is commonly utilized for research purposes exploring the properties of analogous serotonergic psychedelics. It is important to note that 4-HO-MET is not intended for human consumption or clinical use and is strictly for legal laboratory research purposes. Below, we provide an in-depth technical description of this compound, including chemical structure, physical characteristics, potential uses, and recommended handling practices.
Chemical Profile
- IUPAC Name: 3-[2-(Ethylmethylamino)ethyl]-1H-indol-4-ol
- Molecular Formula: C13H18N2O
- Molecular Weight: 218.30 g/mol
- CAS Number: 77872-43-8
- SMILES Identifier: CCN(C)CCc1c[nH]c2c1cc(O)cc2
4-HO-MET is chemically distinct within its class by the addition of an N-methyl and N-ethyl group attached to the ethylamine chain of the base tryptamine structure. The hydroxyl group on the indole ring at the 4th position further contributes to its classification as a hydroxytryptamine derivative.
Physical Characteristics
4-HO-MET typically appears as a fine crystalline or powdered solid. Its color can range from pure white to a light beige hue, depending on the synthesis process and degree of purity. The substance is moderately soluble in polar solvents such as ethanol or water and is stable under typical storage conditions when kept in a cool, dry, and sealed environment.
- Appearance: Fine crystalline or powdered solid
- Solubility: Moderately soluble in water, ethanol, and other polar solvents
- Stability: Stable at room temperature in sealed containers away from light and humidity
Applications in Research
4-HO-MET serves as a valuable compound for scientific research, particularly in studies related to neuropharmacology and psychopharmacology. Researchers often utilize 4-HO-MET to investigate its binding affinity to serotonin (5-HT) receptors, which are implicated in mood, cognition, and perception mechanisms. Due to its similarity to other serotonergic psychedelics, 4-HO-MET is also used to model the effects of such substances in controlled experimental settings.
This compound provides insight into receptor-ligand interactions and aids in enhancing our understanding of how psychoactive compounds affect the central nervous system. Additionally, it is frequently studied for its structural and pharmacological comparison to naturally occurring substances like psilocybin and psilocin.
Handling and Storage Guidelines
When working with 4-HO-MET powder, it is critical to adhere to proper laboratory protocols to ensure safety and maintain the integrity of the material:
- Personal Protective Equipment (PPE): Researchers should wear gloves, safety goggles, and a lab coat to prevent skin or eye contact. Standard laboratory ventilation systems or fume hoods are strongly recommended during handling.
- Storage: Store the compound in a sealed, airtight container away from direct sunlight, heat sources, or high humidity. Ideal storage temperature is below 25°C (77°F).
- Measurement and Handling: Use precision analytical balances for accurate measurements, and avoid direct contact with the substance. All handling should occur in compliance with local laws and regulations.
Legal and Regulatory Considerations
The legal status of 4-HO-MET varies by jurisdiction. While it is not classified as a controlled substance in some countries, others may prohibit its possession or use outside of specific institutional or industrial contexts. Researchers should confirm local regulations prior to acquisition and usage. Importantly, this compound is sold strictly for educational, analytical, and forensic research purposes.
Product Quality and Testing
Each batch of 4-HO-MET powder is rigorously tested to ensure consistency, purity, and quality. Analytical methods such as gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) spectroscopy are employed to confirm molecular structure and identify impurities. Typical purity levels exceed 98%, ensuring researchers receive reliable material for their work. Certificates of Analysis (CoA) are provided with every purchase for verification purposes.
Key Features
- High purity (≥98%) ensures reliable outcomes in research settings
- Stable, powdered form for versatile applications and ease of use
- Carefully synthesized and tested following stringent quality control protocols
- Packaged securely to maintain integrity during storage and shipping
4-HO-MET is distributed exclusively to verifiable research institutions, academic laboratories, or certified industrial entities. This ensures its use remains restricted to settings that align with ethical and scientific standards.
Disclaimer
This product is for research purposes only and is not approved for human or animal use. The manufacturer and distributor assume no liability for improper or unauthorized use of this compound. Researchers are required to comply with all applicable laws and regulations in their region.
By choosing 4-HO-MET powder for your study, you gain access to a high-quality research tool that can advance our understanding of serotonergic systems and related phenomena. Always handle responsibly and prioritize safety in every step of your research process.
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