5F-SGT-151 Powder

5F-SGT-151 Powder is a synthetic cannabinoid product specifically engineered for research and analytical purposes. It is a potent chemical compound that acts on cannabinoid receptors in biological systems, making it a significant subject of study in the fields of forensic science, biochemistry, and pharmacology. This powder is part of the indole-based synthetic cannabinoid family and is considered a next-generation derivative developed to meet advanced research requirements. Here, we provide an in-depth examination of its properties, applications, and storage conditions.

Chemical Composition and Structure

5F-SGT-151 is chemically identified as N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide. Its molecular formula is C21H29FN2O, and its molecular weight is approximately 344.47 g/mol. This compound belongs to the indole-3-carboxamide family and includes a fluoropentyl side chain. The adamantyl group attached to the carboxamide ensures high receptor affinity, enhancing its effectiveness in scientific investigations. The fluorine element in the side chain strengthens molecular stability, making it an ideal candidate for testing in controlled laboratory environments.

Physical Properties

• Form: Fine crystalline powder
• Color: White to off-white
• Purity: ≥ 98% (HPLC tested for research-grade assurance)
• Solubility: Soluble in organic solvents such as ethanol, DMSO, and acetone
• Stability: Maintains chemical integrity under recommended storage conditions

The highly stable and pure form of 5F-SGT-151 Powder makes it suitable for precise analytical assays and controlled studies.

Mechanism of Action

5F-SGT-151 is a potent agonist of CB1 and CB2 receptors found in the endocannabinoid system. Upon binding to these receptors, it produces significant cannabinoid-like effects at a molecular level, aiding researchers in studying receptor functions, signaling pathways, and pharmacodynamics. Due to its high selectivity and precision in targeting cannabinoid receptors, this compound is a valuable resource for understanding cellular response mechanisms and receptor-ligand interactions.

Primary Applications

1. Forensic Analysis:

5F-SGT-151 Powder is commonly used for identifying synthetic cannabinoids in seized samples to aid legal and criminal investigations. Analytical methods such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) often rely on this compound as a reference standard.

2. Pharmacological Research:

This compound is used for investigating the effects of synthetic cannabinoids on CB1 and CB2 receptors. Such studies provide insights into drug-receptor interactions, offering important data on potency, efficacy, and receptor affinity.

3. Toxicological Studies:

Toxicologists employ 5F-SGT-151 to assess its potential physiological effects, metabolic pathways, and safety profiles. These studies help in understanding the implications and potential risks of synthetic cannabinoids.

4. Binding Assays:

Researchers utilize the compound in receptor-binding assays to quantify how strongly it binds to cannabinoid receptors. This data is crucial in comparing the activity profile of different synthetic cannabinoids.

5. Advanced Analytical Techniques:

Laboratories use 5F-SGT-151 in various chromatographic and spectrometric analyses to develop robust testing methods for synthetic cannabinoids in biological samples.

Handling and Storage Instructions

To preserve its chemical integrity and ensure optimal performance, 5F-SGT-151 Powder should be stored in a cool, dry place, away from direct sunlight and exposure to moisture. The recommended storage temperature is -20°C in a tightly sealed container. Researchers handling the compound should wear appropriate personal protective equipment (PPE) such as gloves, lab coats, and safety goggles. It is critical to ensure the workspace is well-ventilated and that proper laboratory protocols for handling chemicals are followed to prevent contamination or accidental exposure.

Quality Assurance

This product undergoes rigorous quality control testing to meet the highest standards required for research-grade chemicals. It is manufactured following strict guidelines to ensure consistency, reliability, and purity. Analytical techniques such as HPLC and NMR are employed to verify the chemical composition, structural integrity, and absence of impurities.

Legal Disclaimer

5F-SGT-151 Powder is strictly intended for research and analytical purposes. It is not approved for human or veterinary use. Purchasers must ensure they comply with all local, state, and federal laws governing the use and possession of synthetic cannabinoids. The product must only be used by qualified professionals in controlled laboratory settings.

Safety Precautions

5F-SGT-151 Powder should not be ingested, inhaled, or brought into contact with skin or eyes. It should be handled using proper laboratory techniques to prevent accidental exposure. A detailed Safety Data Sheet (SDS) is available upon request to provide comprehensive safety and first-aid information.

Summary

5F-SGT-151 Powder is a versatile and reliable synthetic cannabinoid widely used in research applications. Its advanced chemical design, high purity, and reproducibility make it a crucial tool for researchers investigating cannabinoid receptor interactions, pharmacodynamics, forensic identification, and toxicology. By offering precise results in controlled environments, this compound pushes the boundaries of synthetic cannabinoid research, contributing valuable insights to scientific understanding. Researchers are advised to handle the product responsibly and in compliance with applicable regulations.