Bromazolam Powder

Bromazolam Powder is a high-purity research chemical categorized as a thienotriazolodiazepine derivative. Known for its structural similarity to traditional benzodiazepines, Bromazolam enhances research into the pharmacological activities of GABA-A receptor agonists and their interactions in various systems. This compound is distinguished by its chemical composition and potential for application in a range of scientific studies.

Chemical Properties and Specifications

Bromazolam Powder, chemically defined as 8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine, has the molecular formula C16H12BrN3. It possesses a molecular weight of 342.2 g/mol and features a unique brominated structure, which contributes to its distinctive pharmacodynamic and pharmacokinetic characteristics. The compound generally appears as a fine crystalline powder with a white to off-white color, indicating its high level of purity. Purity is typically verified through advanced analytical techniques such as high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy.

Applications in Research

Bromazolam Powder is utilized primarily in laboratory research settings. It demonstrates strong binding activity at the benzodiazepine site of the GABA-A receptor, which is essential for studying the modulation of inhibitory neurotransmitters within the central nervous system (CNS). Its efficiency as a GABA-A receptor modulator allows researchers to explore various CNS-related mechanisms, including sedation, anxiolysis, and anticonvulsant effects.

This compound has been particularly instrumental in studying receptor subtype selectivity. Researchers employ Bromazolam to investigate how minor structural modifications influence receptor binding affinity and efficacy. Its profile supports in-depth studies into the design of diazepine-type compounds targeted at specific CNS disorders, offering insights into therapeutic potential and safety profiles.

Handling and Storage Guidelines

Bromazolam Powder is a sensitive material and should be handled cautiously in controlled laboratory environments. It is recommended to store the chemical in a cool, dry location, away from direct sunlight, heat, and moisture. For ensuring chemical stability, storage temperatures should ideally remain below 25°C, and the substance should be kept in an airtight container to prevent contamination or degradation.

Researchers handling Bromazolam Powder must adhere to standard laboratory safety protocols. Appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coats, should always be worn. It is crucial to avoid direct inhalation, ingestion, or skin contact. Work in a well-ventilated laboratory or, where necessary, under a fume hood to ensure minimal exposure to airborne particles or vapors.

Legal and Regulatory Considerations

Bromazolam is classified as a research chemical and is not intended for human or veterinary use. Its distribution, possession, and application are subject to regulatory provisions that vary depending on the region or country. Researchers are responsible for confirming their compliance with all relevant laws and guidelines before obtaining and utilizing this compound. Unauthorized use or misuse of Bromazolam is strictly prohibited.

Safety and Risk Management

Though its precise toxicological effects remain under investigation, researchers should treat Bromazolam Powder as potentially hazardous. Material Safety Data Sheets (MSDS) or equivalent documentation should be reviewed prior to its use to understand the associated risks and recommended mitigation measures. Accidental exposure should be addressed promptly by medical professionals, and all handlers should have access to first-response guidance in case of spills or emergencies.

It is important to note that Bromazolam, like other benzodiazepine analogues, may exhibit interactions with various CNS-active substances. Researchers should document all relevant test conditions to ensure accurate results while maintaining laboratory safety.

Packaging and Availability

Bromazolam Powder is available in a variety of quantities to suit different research requirements. Commonly offered packaging sizes range from small-scale amounts, such as 1 gram, for exploratory testing, to bulk orders for long-term or industrial research purposes.

Disclaimer

Bromazolam Powder is strictly intended for scientific research and analytical purposes and must be utilized solely by qualified professionals in appropriate settings. Any use outside these parameters is strongly discouraged and may be unlawful. This product is not approved for diagnostic, therapeutic, or recreational purposes.

By providing top-grade Bromazolam Powder, researchers are empowered to advance their studies in pharmaceutical development, CNS pharmacology, and receptor interactions, contributing to a growing body of scientific knowledge and innovation.