DCK (Deschloroketamine) – The Iconic Arylcyclohexylamine
For researchers studying the pharmacology of dissociatives, DCK (Deschloroketamine), also known as DXE, needs little introduction. It is widely regarded as one of the most significant structural analogues of Ketamine ever synthesized, offering a cleaner, more potent research profile that has made it a staple in laboratories across Europe.
EuroChems is proud to offer high-purity DCK HCL (Hydrochloride) crystals, synthesized to meet the rigorous demands of modern spectroscopy and receptor binding analysis.
The Chemistry: Less is More
Structurally, DCK is defined by simplicity. It is officially known as 2′-Oxo-PCM (2-Phenyl-2-(methylamino)cyclohexanone).
The Difference: As the name implies, Des-chloro-ketamine is essentially the Ketamine molecule with the chlorine atom at the phenyl ring removed (substituted with a hydrogen atom).
The Result: This slight structural tweak drastically alters its physicochemical properties. Research indicates that DCK exhibits a higher potency by weight and a significantly longer duration of action compared to its chlorinated parent compound.
Research Profile & Applications
In the lab, DCK is prized for its unique interaction with NMDA receptors. It is distinct from 2-FDCK and Canetone (2F-NENDCK) due to its lack of a halogen substitution, making it an essential control sample for studying Structure-Activity Relationships (SAR).
Key Research Characteristics:
High Potency: Requires precise milligram-scale titration.
Extended Duration: Studies suggest a research window significantly longer than Ketamine or 2-FDCK.
Antibacterial Properties: Literature notes that DCK possesses distinct antibiotic properties, adding a unique variable to biological studies.
Why Source DCK from EuroChems?
In a market flooded with varying qualities, purity is paramount.
verified Purity: Our DCK batches are tested via NMR to ensure >98% purity, free from synthesis byproducts.
Stable Crystal Form: Supplied as robust HCL crystals, ideal for long-term storage and stable measurement.
Secure Logistics: Shipped rapidly and discreetly from our EU hub.
Safety & Compliance: This product is strictly for in-vitro laboratory research and forensic analysis. It is NOT for human consumption or veterinary use. Please verify the legal status of Deschloroketamine in your jurisdiction before purchasing.




