Overview
Diclazepam, also known as 2’-chloro-diazepam, is a research chemical belonging to the benzodiazepine class. It is a derivative of diazepam, sharing similar structural properties but with subtle differences that enhance its distinct pharmacological profile. Diclazepam is primarily intended for laboratory and analytical use to explore its interaction with various receptors and investigate its functional properties within controlled research environments. It is not approved for human or veterinary use.
Chemical Properties
- Chemical Name: 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Molecular Formula: C16H12ClN2O
- Molecular Weight: 298.7 g/mol
- CAS Number: 2894-68-0
Diclazepam is a white crystalline powder known for its high purity and stability under standard laboratory conditions. The compound demonstrates solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), with low solubility in water. These properties make it suitable for use in various testing mediums and advanced chemical analysis.
Mechanism of Action
Diclazepam interacts with the gamma-aminobutyric acid (GABA-A) receptors in the central nervous system as a positive allosteric modulator. By binding to these receptor sites, it enhances the effects of GABA, an inhibitory neurotransmitter responsible for calming neural activity. This mechanism of action is of particular interest to researchers studying neurological pathways, receptor pharmacodynamics, and compound specificity for related scientific advancements.
Applications in Research
Diclazepam powder is commonly employed in pharmacological and toxicological research projects. Key areas of investigation include:
- Binding Affinity Studies: Evaluating the interaction between Diclazepam and benzodiazepine receptor subtypes to understand its specificity and potency.
- Metabolic Profiling: Exploring the metabolic pathways of Diclazepam to identify its metabolites, enzymatic breakdown, and impact on target systems.
- Structure-Activity Relationship (SAR) Analysis: Analyzing how structural variations influence the functional characteristics of Diclazepam compared to related benzodiazepines such as diazepam or clonazepam.
- Neurological Research: Investigating its potential effects on GABAergic systems, focusing on inhibitory neurotransmission and synaptic modulation.
Safety and Handling
When working with Diclazepam powder, adherence to stringent laboratory safety protocols is essential. The compound should only be handled by individuals trained in chemical research and equipped with appropriate personal protective equipment (PPE), including gloves, lab coats, and safety goggles. Work should be conducted in a well-ventilated laboratory or fume hood to prevent accidental inhalation or exposure. Additionally, any spills or contact with skin should be addressed immediately by following standard chemical decontamination procedures.
- Storage: Store Diclazepam powder in a cool, dry place, away from direct sunlight and moisture. It is best stored in an airtight container to preserve its stability and prevent cross-contamination. Recommended storage temperature is between 2-8°C.
- Disposal: Dispose of unused material and waste in accordance with local regulations for chemical disposal to ensure environmental safety.
Purity and Quality Assurance
Each batch of Diclazepam powder undergoes rigorous quality control processes to ensure the consistency, purity, and reliability of the substance.
Legal Disclaimer
It is important to note that Diclazepam is strictly intended for research purposes and is not suitable for human or animal consumption. Buyers are responsible for complying with all applicable laws and regulations regarding the use, handling, and possession of the compound. Researchers must exercise caution and due diligence when conducting experiments involving this substance.
Packaging and Availability
Diclazepam powder is supplied in secure, tamper-evident containers to maintain product integrity during transit and storage. Packaging sizes are available in various quantities to meet the diverse needs of research facilities, ranging from small sample units to bulk orders. For specific availability, shipping times, and packaging options, please contact us on our helpdesk.
Technical Support
Comprehensive technical documentation and resources are available to support researchers in their work with Diclazepam powder. Should you require further information, safety data sheets (SDS), or clarification regarding product specifications, our team of experts is available to assist. Please reach out to the technical support team for detailed inquiries or assistance with experimental setups.
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