Norflurazepam Pellets (5mg)

Norflurazepam pellets (5mg) are pharmaceutical-grade compounds specifically manufactured for research and analytical purposes. These pellets are composed of norflurazepam, a benzodiazepine derivative known for its long half-life and powerful pharmacological properties. Primarily, norflurazepam is investigated in preclinical research and laboratory settings to study its interaction with the central nervous system and its mechanism of action as a gamma-aminobutyric acid (GABA) receptor modulator.

Composition and Packaging

Each pellet contains 5mg of high-purity norflurazepam as the active ingredient, blended with pharmacologically inert fillers to ensure uniformity and stability. The formulation is synthesized under stringent quality controls to guarantee consistent dosing and precise measurements. Norflurazepam pellets are packaged in airtight, UV-resistant containers to preserve chemical integrity and prevent degradation due to exposure to environmental factors such as light, air, and humidity.

Chemical Properties

Norflurazepam is a metabolite of several benzodiazepines, including flurazepam, and is classified as a 1,4-benzodiazepine. It has the molecular formula C15H10ClFN2O and a molecular weight of 288.7 g/mol. Featuring a high affinity for the benzodiazepine binding site on GABAA receptors, norflurazepam’s potency and extended half-life make it a distinctive compound in research focused on sedative, anxiolytic, and hypnotic effects.

The compound is white to off-white in appearance, crystalline in form, and exhibits solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO). Its stability under diverse laboratory conditions ensures reliable results in experimental setups.

Key Applications in Research

Norflurazepam is widely utilized in neuroscientific and pharmacological research to explore its effects on the GABAergic system. Some of the most notable applications are outlined below:

1. Receptor Binding Studies

Norflurazepam is used to examine the binding affinity and interaction of benzodiazepines with GABAA receptors. These studies contribute to a deeper understanding of the mechanisms underlying the sedative and anxiolytic properties of benzodiazepines.

2. Pharmacokinetic Analysis

Researchers use norflurazepam to model drug metabolism, distribution, and elimination within biological systems. Its extended half-life allows detailed investigation into benzodiazepine persistence and potential accumulation in tissues.

3. Behavioral Studies

Preclinical experiments often involve norflurazepam to assess its impact on behavior in animal models, including sedation, reduced motor activity, and potential alterations in anxiety-like behaviors.

4. Compound Screening and Comparative Studies

Norflurazepam serves as a benchmark in comparison studies to evaluate the potency, efficacy, and receptor selectivity of newly developed benzodiazepine analogs.

Handling and Storage

Proper precautions must be undertaken when handling norflurazepam pellets due to their pharmacologically active nature. They should be stored in a cool (15-25°C), dry environment, away from direct sunlight, heat, or moisture to maintain their stability and efficacy. Laboratory personnel must use standard personal protective equipment (PPE) such as gloves and safety goggles while handling the product.

Legal Considerations

Norflurazepam is classified as a research chemical and is strictly intended for forensic and scientific research purposes. It is not approved for human or veterinary use. Users must abide by all applicable local, state, and federal regulations pertaining to the acquisition, handling, and application of norflurazepam. Any deviation from authorized use may result in legal and regulatory consequences.

Disclaimer

This product description is meant solely for informational purposes. Norflurazepam pellets (5mg) are not designed for consumption by humans or animals. The buyer assumes all responsibility for ensuring compliance with local laws governing the use of research chemicals. All experiments involving norflurazepam must be conducted in well-equipped facilities by trained professionals.

Norflurazepam pellets (5mg) represent a high-quality and reliable resource for researchers investigating the pharmacodynamics and pharmacokinetics of benzodiazepine-derived compounds. By adhering to recommended storage, handling, and legal guidelines, researchers can harness the full potential of this compound for advancing scientific knowledge in pharmacology and neuroscience.