Pyrazolam Pellets (3mg)

Pyrazolam Pellets (3mg) are a research chemical product designed specifically for laboratory and research purposes. Containing 3mg of high-purity Pyrazolam per pellet, this compound is notable for its profile as a triazolobenzodiazepine derivative. Pyrazolam, first synthesized in 1970, is a non-sedating benzodiazepine analog that has been studied extensively for its binding affinity, pharmacokinetics, and receptor modulation effects. Its primary mechanism of action involves selective affinity for GABA-A receptors, particularly at sites associated with anxiolytic and muscle-relaxant properties.

Chemical Composition and Structure

Each pellet contains 3mg of Pyrazolam (CAS Number 95737-68-1), which has a molecular formula of C16H12BrN5. Pyrazolam is characterized by a bromine substituent that enhances its receptor affinity and metabolic stability. Its structural backbone includes a triazolo ring fused with a diazepine ring, making it chemically distinct compared to traditional benzodiazepines. The compound has a molecular weight of 354.21 g/mol and demonstrates optimal solubility in organic solvents, ensuring precise measurements during research applications.

Intended Use and Applications

Pyrazolam Pellets are strictly intended for scientific research and in vitro laboratory testing. They are commonly investigated in studies involving receptor binding affinity, where it has been found to exhibit a high binding selectivity for α1, α2, α3, and α5 subunits of the GABA-A receptor complex. These properties make Pyrazolam a useful compound for studies on receptor modulation, pharmacodynamics, and potential anxiolytic effects. Importantly, Pyrazolam lacks sedative properties, which distinguishes its profile from other compounds in the benzodiazepine class and makes it a valuable tool for focused investigations.

Safety and Handling

Proper storage and handling of Pyrazolam Pellets are critical for maintaining their stability and integrity. The pellets should be stored in a cool, dry environment away from direct sunlight or excessive heat. Researchers are advised to use Personal Protective Equipment (PPE), such as gloves and laboratory eyewear, when handling the material. Due to the potency of the active compound, handling protocols must maintain strict compliance with standard laboratory safety guidelines to prevent accidental exposure or misuse. Additionally, researchers should avoid manual handling of the pellets and rely on precision instruments such as forceps or automated dispensers to ensure accurate dosing.

Analytical Properties

Pyrazolam exhibits a high degree of purity and stability, making it ideal for various analytical techniques, including high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR). These methods allow researchers to confirm the composition and molecular structure of the compound, offering reliable data for experimental setups. Pyrazolam Pellets have a predictable dissolution profile in organic solvents, facilitating controlled studies for receptor binding or competitive inhibition assays. Furthermore, its non-sedating nature offers an opportunity for researchers to study anxiolytic pathways without the confounding effects of sedation.

Storage and Shelf Life

To maintain optimal potency and reactivity, Pyrazolam Pellets should be stored at temperatures below 25°C, ideally in a nitrogen-filled environment to minimize oxidation risks. The shelf life of the pellets is typically two years from the date of manufacture when stored under proper conditions. Visible degradation, discoloration, or chipping of the pellets should be noted as indicators that the product may no longer meet experimental grade standards. Regular quality control analysis is recommended for long-term studies where consistent compound integrity is required.

Regulatory Compliance

Pyrazolam Pellets (3mg) adhere to all relevant regulatory standards for research chemicals. Users are reminded that these pellets are not intended for human consumption or medical applications. All research activities involving Pyrazolam should be conducted under the supervision of qualified personnel in a controlled research environment. Additionally, it is essential to ensure all procurement and use of Pyrazolam comply with local, state, and federal regulations governing research chemicals.

Key Features

• Purity: Manufactured to meet strict industry standards for research-grade compounds.
• Potency: Each pellet contains an exact dosage of 3mg for consistent and reproducible results.
• Non-Sedating: Unlike traditional benzodiazepines, Pyrazolam demonstrates minimal to no sedative effects.
• Selective Binding: Exhibits high affinity for specific GABA-A receptor subunits, making it ideal for targeted research.
• Stability: Long shelf life when stored properly, ensuring reliable performance for extended study timelines.

Additional Notes

Researchers are urged to utilize this compound respectfully and responsibly, with adherence to all legal and ethical standards. Pyrazolam Pellets (3mg) represent a valuable addition to modern pharmacological and receptor-specific research.

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