4-HO-MET

4-HO-MET é uma triptamina substituída utilizada em pesquisa farmacológica do receptor de serotonina. Este composto serve como padrão de referência em química analítica e é valioso para estudar mecanismos de neurotransmissores serotoninérgicos.

The history of 4-HO-MET is rooted in the extensive research into tryptamine compounds that began with the isolation and characterization of naturally occurring indole alkaloids. Scientists have long been fascinated by tryptamines due to their structural similarity to serotonin (5-HT) and their profound effects on consciousness and perception. Research into 4-HO-MET represents a continuation of this scientific tradition. Following Alexander Shulgin's pioneering work documenting substituted tryptamines in his research notebooks and publications, modern chemists have synthesized and characterized numerous analogs to understand structure-activity relationships. 4-HO-MET emerged as a compound of interest for its unique pharmacological profile and potential applications in neuroscience research. The compound has been studied for its interactions with various serotonin receptor subtypes. Today, 4-HO-MET serves as an important research tool in laboratories studying serotonin pharmacology, receptor binding mechanisms, and the neural correlates of altered states of consciousness. Its use in analytical chemistry as a reference standard has contributed to advances in detection methods and quality control protocols for novel psychoactive substances.

As a tryptamine compound, 4-HO-MET structurally resembles serotonin (5-HT) and interacts with various serotonin receptor subtypes. This interaction modulates neurotransmission pathways, making it valuable for pharmacological research into indolealkylamine function.

4-HO-MET holds significant value in scientific research due to its well-characterized properties and legal accessibility in several jurisdictions. This enables comprehensive pharmacological studies and analytical method development.

High-purity 4-HO-MET (≥98% by HPLC) serves as a crucial reference standard in research laboratories, quality control testing, and academic research settings. Its consistent quality makes it ideal for method development and validation.