Pregled
AP-237 je raziskovalna opioidna spojina, ki se uporablja v študijah farmakologije opioidnih receptorjev (mu, delta, kappa). Ta spojina je dragocena za raziskave obvladovanja bolečin in kot analitični standard.
The history of AP-237 is connected to opioid research extending from morphine's isolation in 1804 to modern synthetic opioid development. Scientists have extensively investigated how structural modifications to opioid scaffolds affect mu, delta, and kappa opioid receptor binding and activity. AP-237 represents a product of this ongoing research into novel opioid compounds. Research into synthetic opioids has focused on understanding structure-activity relationships at opioid receptors, metabolism, and pharmacokinetics. AP-237 emerged as a compound of interest for studying these relationships and for use as an analytical reference standard in forensic toxicology. The compound has been characterized using advanced analytical techniques including mass spectrometry and chromatography. Modern research applications of AP-237 include studies on opioid receptor pharmacology, analgesic mechanisms, and the development of detection methods for novel opioids in biological samples. The compound serves as a valuable tool in analytical chemistry and pain research, contributing to our understanding of opioid receptor function and pharmaceutical development.
AP-237 acts primarily as an agonist at mu-opioid receptors, producing analgesic effects. This mechanism makes it valuable for research on opioid receptor pharmacology, pain management, and forensic detection method development.
AP-237 holds significant value in scientific research due to its well-characterized properties and legal accessibility in several jurisdictions. This enables comprehensive pharmacological studies and analytical method development.
High-purity AP-237 (≥98% by HPLC) serves as a crucial reference standard in research laboratories, quality control testing, and academic research settings. Its consistent quality makes it ideal for method development and validation.
Tehnične Specifikacije
Zakaj Raziskovalci Izbirajo AP-237
🔬Opioid Receptor Research
AP-237 serves as a reference material for studying mu, delta, and kappa opioid receptor pharmacology. Its use enables analytical method development for novel opioid compounds and metabolites.
🧬Pain Research Studies
Researchers investigate AP-237 to understand structure-activity relationships in opioid analgesics and their effects on pain pathways, supporting pharmaceutical development.
📊Forensic Applications
High-purity AP-237 is essential for forensic toxicology laboratories developing detection methods for novel opioids in biological samples and quality control protocols.
Raziskovalne aplikacije
Pomembno Opozorilo: Ta spojina je namenjena izključno raziskovalnim in analitičnim namenom. Ni za človeško uporabo.
Kemijske Lastnosti
Podatki o Topnosti
Analitične metode
Zunanje Podatkovne Baze
Varnost in Informacije o Nevarnostih
Hazard Statements (H):
- •H302: Harmful if swallowed
- •H315: Causes skin irritation
- •H319: Causes serious eye irritation
- •H335: May cause respiratory irritation
Precautionary Statements (P):
- •P261: Avoid breathing dust/fume/gas/mist/vapors/spray
- •P264: Wash hands thoroughly after handling
- •P280: Wear protective gloves/protective clothing/eye protection/face protection
- •P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell
Pogosti Učinki
Pravni status po državi
Kliknite na državo za podrobne pravne informacije in podrobnosti o pošiljanju.
Pogosto zastavljena vprašanja
Q:What is AP-237 used for in research?
AP-237 is primarily used as an analytical reference standard in forensic toxicology, pharmacological research, quality control testing, and method development. It is NOT intended for human or veterinary use.
Q:How should AP-237 be stored?
Store AP-237 at -20°C in a dark, dry environment. Protect from light and moisture to maintain stability. When stored properly, research chemicals have a shelf life of approximately 2 years. Always use amber glass vials with proper sealing.
Q:What analytical methods are used to test AP-237 purity?
High-Performance Liquid Chromatography with UV detection (HPLC-UV) is the primary method for purity analysis. Additional confirmation methods include Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Mass Spectrometry (LC-MS/MS), and Nuclear Magnetic Resonance (NMR) spectroscopy.
Q:What is the minimum purity guaranteed for EuroChems AP-237?
All EuroChems AP-237 products are guaranteed to be ≥98% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis (COA) confirming purity specifications.
Povezane Raziskave
Viri
Varnostno Obvestilo
Samo za raziskovalne namene. NI ZA ČLOVEŠKO PORABO. Zahteva pravilno laboratorijsko ravnanje.